Clinically Relevant Insights
Tests analyze risk variants identified from genome-wide studies of >100K patients with breast or prostate cancer.

Map the landscape of prostate and breast cancer risk using whole-genome sequencing to calculate personalized, clinically integrated risk scores to support proactive care plans.
genetic risk factors analyzed
risk reported
turnaround time from samples received
sample types accepted

Integrated Risk tests combine polygenic risk scores (PRS) from whole-genome sequencing with clinical inputs from a patient's health history to reveal cancer risks that traditional assessments and single-gene risk screening may miss. As science advances and clinical profiles evolve, the same whole-genome dataset can be reanalyzed for new insights — no new sample required.
Tests analyze risk variants identified from genome-wide studies of >100K patients with breast or prostate cancer.
Results include clear metrics and next steps aligned with breast or prostate cancer guidelines.
Proprietary ancestry decomposition technology enables accurate risk prediction across diverse populations, validated in >130K patients with breast or prostate cancer.
of individuals do not have a single-gene cancer condition
But may still carry polygenic cancer risk.¹
of breast cancers have a genetic cause undetected by single-gene analysis
Single-gene tests miss these genetic risk factors.²
of breast and prostate cancer risk is heritable
Detectable as genetic markers by the iPRS test.³,⁴
1. Garber JE, Offit K. J Clin Oncol. 2005;23:276–292. 2. Wendt C, Margolin S. Acta Oncologica. 2019;58(2):135–146. 3. Sokolova A, et al. Histopathology. 4. Zero Prostate Cancer. ZERO. 2025.
Polygenic risk scores combined with clinical factors deliver highly accurate, personalized risk scores for serious cancers — capturing a layer of risk that single-gene testing alone can miss.
Combines whole-genome insights, personal and family history, and clinical factors to provide a 5-year and lifetime risk estimate for developing breast cancer.
Learn MoreCombines whole-genome insights, personal and family history, and clinical factors to provide a 10-year and/or lifetime risk estimate for developing prostate cancer.
Learn MoreLeverages whole-genome sequencing for comprehensive insights across coding and non-coding regions, with re-analysis on the same sample as new scores launch.
Uses high-coverage exome plus low-coverage whole-genome sequencing — a cost-effective option for preventative health decisions, with re-analysis on the same sample as new scores launch.
From samples received, most results are delivered in 5 to 6 weeks. Follow-up testing or re-requisitions for existing MyOme patients are typically completed in under 2 weeks, often within a few days.
Integrated Risk tests are intended as proactive risk screening tools — they are not diagnostic tests.
Integrated Risk tests detect millions of polygenic risk factors — they do not detect high impact variants associated with monogenic cancers (e.g., BRCA1 and BRCA2).
Some individuals with high scores won't develop cancer, and some with low scores will.
We're here at every step — from ordering and sample collection to interpreting results with your patients.