Our Approach
A comprehensive approach for lifelong insights
We utilize the whole genome to provide clinically actionable insights and guide health decisions throughout a patient's life. To accomplish our goal, we combine genomic sequencing and industry-leading risk scoring with a platform that’s easy to integrate with routine care. Support is provided throughout the whole process, including access to genetic counselors to help patients and providers understand results.
A whole genome approach
Rather than limiting our genetic sequencing to a small selection of coding regions, MyOme sequences the whole genome. That means we can provide better clinical utility, with insights for common conditions alongside rare, single-gene diseases. It also allows us to use one sample to provide access to an expanding menu of tests, and even re-query a patient's genome as healthcare needs change and new information about genomics is discovered.
30x Whole Genome Sequencing (WGS)
30x WGS is a clinical-grade test that sequences the entire genome at an average depth of 30 reads per base, ensuring high accuracy and reliability. As the gold standard in genetic testing, it enables comprehensive detection of SNVs, indels, structural variants, and copy number changes. Clinically, 30x WGS supports disease diagnosis, risk assessment, and treatment decisions by providing a more complete view of genetic factors than targeted tests.
Blended Genome-Exome Sequencing (BGE)
BGE Sequencing combines low-pass WGS and deeper coverage whole exome sequencing (WES), allowing high quality imputation of common variants across the genome as well as detection of rare coding variants across the exome region, from a single sample.
Industry-leading Integrated Polygenic Risk Scores (iPRS™)
For our iPRS, we integrate clinical risk factors with millions of genetic variants that confer risk for common health conditions — providing a more accurate assessment of patient risk than either source can provide alone.
We adjust for differences in genetics due to ancestry and utilize continuous ancestry decomposition to account for admixture in individuals. This information is integrated with the patient’s risk based on clinical measures, such as the Tyrer-Cuzick model for breast cancer or the Atherosclerotic Cardiovascular Disease Pooled Cohort Equations for coronary artery disease. As a result, our PRS offers unique, holistic, clinically relevant reports.
A streamlined workflow
Our process was designed to be customizable and easy to implement. Ordering is simple through our provider portal, with kits available for buccal, saliva, or blood collection. Once we’ve received the sample and conducted sequencing and analysis, we deliver a report that includes actionable clinical insights, with options for independent provider review and an easy-to-understand independent provider note that can be shared with patients.
Genetic counseling for continued support
Genetic testing is more than a report. We offer complimentary access to genetic counseling from an independent provider, connecting patients with the support they need to understand their results and make the healthcare decisions that are right for them.
Order a test
We make it easy for providers to order a MyOme test through the MyOme portal — and one sample provides access to a broad menu of tests. Get more information on how to order a MyOme test and get the process started.
