Our approach

A comprehensive approach for lifelong insights

We utilize the whole genome to provide clinically actionable insights and guide health decisions throughout a patient's life — combining genomic sequencing and industry-leading risk scoring with a platform that's easy to integrate with routine care.

Whole genome

sequenced, not a fixed panel

One sample

blood or buccal, re-queried over time

Integrated Risk

genetics plus clinical risk factors

Counseling

included with every result

Sequencing

A whole-genome approach

Rather than limiting our genetic sequencing to a small selection of coding regions, MyOme sequences the whole genome. That means we can provide better clinical utility, with insights for common conditions alongside rare, single-gene diseases.

It also allows us to use one sample to provide access to an expanding menu of tests, and even re-query a patient's genome as healthcare needs change and new information about genomics is discovered.

Illustration of MyOme's whole-genome approach

30x whole-genome sequencing

A clinical-grade test that sequences the entire genome at an average depth of 30 reads per base, ensuring high accuracy and reliability. As the gold standard in genetic testing, it enables comprehensive detection of SNVs, indels, structural variants, and copy number changes — supporting diagnosis, risk assessment, and treatment decisions with a more complete view than targeted tests.

Blended genome-exome sequencing

BGE combines low-pass whole-genome sequencing with deeper-coverage whole-exome sequencing, allowing high quality imputation of common variants across the genome as well as detection of rare coding variants across the exome region — all from a single sequence.

Risk modeling

Industry-leading Integrated Risk

We integrate clinical risk factors with millions of genetic variants that confer risk for common health conditions — providing a more accurate assessment of patient risk than either source can provide alone.

We adjust for differences in genetics due to ancestry and use continuous ancestry decomposition to account for admixture in individuals. That information is integrated with the patient's risk based on clinical measures — such as the Tyrer-Cuzick model for breast cancer or the ASCVD Pooled Cohort Equations for coronary artery disease. The result is a unique, holistic, clinically relevant report.

Workflow

A streamlined workflow

Our process was designed to be customizable and easy to implement. Ordering is simple through our provider portal, with kits available for buccal or blood collection.

01

Order

Providers order through the MyOme portal in a few clicks.

02

Collect

Kits are available for buccal or blood collection.

03

Sequence and analyze

We sequence the genome and run analysis in our CLIA-certified, CAP-accredited lab.

04

Report and review

A report with actionable clinical insights, with options for independent provider review and a patient-friendly note.

Support

Genetic counseling for continued support

Genetic testing is more than a report. We offer complimentary access to genetic counseling from an independent provider, connecting patients with the support they need to understand their results and make the healthcare decisions that are right for them.

  • Board-certified genetic counselors
  • Independent provider review
  • Patient-friendly summary notes

Order a test

We make it easy for providers to order a MyOme test through the MyOme portal — and one sample provides access to a broad menu of tests.