Senior Bioinformatics Scientist

About MyOme

We are a Series A, investor backed personalized medicine company bringing genomics to the masses. MyOme is dedicated to improving our customers’ lives through genomics and personalized medicine. MyOme provides its customers with comprehensive information about genetic factors that influence personal risk for disease, with a user-centric delivery model.

Job Description

MyOme is looking for a world class biostatistician / bioinformatician to join our team and impact the way genetic tests inform people about their health risks. Join an early stage startup with seasoned entrepreneurs and help build family planning and personal health platforms. You will collaborate with the research teams to develop polygenic risk score models in the context of family health and in vitro fertilization. We are looking for an experienced statistician/biostatistician, bioinformatician, or data scientist with a strong background in human genetics. Please send your CV to akumar@myome.com. Please include a brief note telling us why you are interested in this position.

Responsibilities

 

  • Work with bioinformaticians and engineers to develop and implement polygenic risk score models.
  • Build and evaluate predictive models on very large genetic datasets using known techniques such as LDpred or novel algorithms.
  • Design and implement quality control processes around data sources used and data validation processes.
  • Work with our Clinical Lab Director to make sure all algorithms comply with regulatory standards.

Required Skills

 

  • Master’s degree or PhD in computational biology, statistics, computer science or a related field.
  • Preferred: 3+ years experience in academia or industry analyzing large datasets.
  • Background in statistics or algorithm development with applications to human genetics.
  • Familiarity with large genetic datasets such as UK Biobank, eMerge, and dbGAP.
  • Strong coding skills in Python or R.
  • Ability to implement new tools and evaluate open source tools quickly.
  • Self starter in statistics and bioinformatics contexts and ability to work in an interdisciplinary team.
  • Excellent communication skills. Skills and capabilities:
  • 3 years experience using common genomics tools such as plink, Beagle, hail, minimac, samtools, vcftools, bcftools.
  • 1 years experience in building polygenic risk models, adjusting models to different populations.
  • Experience in integrating genomics, proteomics, genotyping and sequencing data types.
  • 2 years experience managing large datasets and computational tasks in a cloud environment (AWS or GCP).
  • Solid understanding of the Linux environment. Physical Demands & Work Environment
  • Duties are typically performed in an office setting when not in a pandemic.
  • Duties may require working outside normal working hours (evenings and weekends) at times, e.g. to accommodate work across time-zones.