Job Opportunities

As the onsite General Supervisor, you will lead laboratory operations in both R&D and clinical processes. You will combine your technical skills, equipment and reagent management expertise, and passion for good laboratory practices to help build a high quality and efficient laboratory, with the clinical operations compliant to CLIA and internal policies. The scope of the work includes onsite experiment planning, execution, and write up; sample collection kit assembly; shipping and tracking of samples; coordination of at-home phlebotomy; and processing of clinical samples and coordination with MyOme’s reference laboratories. Your temperament should be nimble, flexible, pragmatic, and collaborative.

Key Responsibilities

• Responsible for managing laboratory operations and functions, including both R&D and Clinical
  • Participation in IRB-approved research study processes including, but not limited to, preparation of sample collection kits, coordination of at-home phlebotomy service, shipping and coordination of samples
  • Participation in R&D experiments for exploration or development of new technical platforms
  • Participation in assay development and optimization processes
  • Management of overall laboratory functions, in compliance with CLIA and COLA, as applicable
    • Materials inventory system
    • Equipment management system, including equipment maintenance and calibration requirements
    • Sample inventory and storage system
• Responsible for handling patient samples and performing established testing procedures as needed.
• Provide onsite day-to-day supervision of testing personnel when patient testing is occurring. The onsite general supervisor must be responsible for the proper performance of all laboratory procedures.
  • Accessible to laboratory personnel at all times during clinical operations, to provide on-site consultation to resolve technical problems in accordance with policies and procedures.
  • Responsible for day-to-day supervision and oversight of the clinical laboratory operation and personnel performing testing
    • Be responsible for providing day-to-day supervision of high complexity test performance by testing personnel;
    • Be responsible for direct supervision of non-licensed personnel by licensed personnel, as appropriate;
    • Be responsible for ensuring appropriate inventory and management systems are established and maintained to support clinical testing
    • Be responsible for monitoring test analyses and specimen examinations to ensure that acceptable levels of analytic performance are maintained;
    • Be responsible for maintaining and securing patient information in accordance with HIPAA regulations and internal policies;
    • Perform a quality assurance review and document the review process by signing off on all quality control and preventive maintenance procedures and forms;
    • Assure that all remedial actions are taken whenever test systems deviate from the laboratory’s established performance specifications;
    • Ensure that test results are not reported until all corrective actions have been taken and the test system is properly functioning;
    • Provide orientation to laboratory personnel; and
    • Train and evaluate the competency of all clinical laboratory personnel and assure that the staff maintain their competency to perform test procedures and report test results promptly, accurately and proficiently.

Ideal Skills and Experience

• Minimum Bachelor of Science Degree in Medical Technology, Biology, or Chemistry.
• Licensed in the state of California as a Clinical Laboratory Scientist, Generalist or (limited) licensed as a Clinical Genetics Molecular Biologist Scientist (CGMBS)
• Has at least 2 years of laboratory testing experience in high complexity testing involving molecular genetics
• Highly preferable to have previous experience in managing clinical laboratory personnel and operations management
• Highly preferable to have experience with regulatory and accreditation of laboratory operations per CLIA and in CAP, COLA, and NYSDOH – CLEP.
• Must have the following knowledge, skills, and abilities
  • Knowledge of clinical laboratory services.
  • Strong organizational and interpersonal skills.
  • Ability to determine appropriate course of action in more complex situations.
  • Ability to work independently, exercise creativity, be attentive to detail, and maintain a positive attitude.
  • Ability to manage multiple and simultaneous responsibilities and to prioritize scheduling of work.
  •  Ability to maintain confidentiality of all medical, financial, and legal information.
  • Ability to complete work assignments accurately and in a timely manner.
  • Ability to communicate effectively, both orally and in writing.
  • Ability to handle difficult situations involving patients, physicians, or others in a professional manner
  • Excellent communication, team player, organizational and time management skills are essential.
  • Ability to work in a fast-paced environment both independently and as a member of a team
  • Strong computer skills with a working knowledge of Microsoft Office Suite (Excel, PowerPoint, Word, etc.)

Hiring Manager

Donna Hongo, Head of Quality, dhongo@myome.com

As the Lead NGS Technician, you will lead laboratory operations under R&D and assist with clinical processes as needed. You will combine your technical skills, equipment and reagent management expertise, and passion for good laboratory practices to help build a high quality and efficient laboratory, utilizing new technologies and laboratory applications. The scope of the work includes onsite experiment planning, execution, and write up; sample collection kit assembly; shipping and tracking of samples; coordination of at-home phlebotomy; and processing of clinical samples under the direction of the general supervisor and coordination with MyOme’s reference laboratories. Your temperament should be nimble, flexible, pragmatic, and collaborative.

Key Responsibilities

• Perform bench level laboratory work, which includes, performing DNA extraction, performing calculations, preparing reagents, operating analytical instruments, and maintaining accurate records in compliance with internal SOPs and external regulations. 
• Assume responsibility for general laboratory maintenance and housekeeping, including receiving and cataloguing of samples, organization and purchasing of laboratory reagents, working with customers/vendors, keeping track of deliveries, maintaining laboratory stocks, and participating in technology development. 
• Organize lab protocols, manuals, MSDS patient sample records, and other materials. 
• Facilitate adherence to lab maintenance and safety procedures. 
• Provide timely feedback regarding lab issues. 
• Maintain impartial and professional relationships with all lab members. 
• Serve as lab liaison for Facilities.
• Work independently or under the guidance of a remote manager.
• Maintain contact with external or internal customers as required to furnish or obtain information or reports, to provide services, or resolve day-to-day problems. 
• Utilize literature reviews, protocols, networking and prior laboratory experience to assist with experimental design, assay development, and workflow optimization. 
• May train other laboratory personnel. 
• Perform other duties as assigned.

Ideal Skills and Experience

• Bachelor’s degree in biology, biotechnology, or similar field. 
• Experience with DNA extraction from blood and/or saliva required
• Standard molecular biology lab techniques: PCR, qPCR, gel electrophoresis
• Experience performing nucleic acid QA / QC assays including nanodrop, qubit, bioanalyzer / Tapestation etc. 
• Ability to follow written and verbal instruction and apply good documentation practices. 
• Comfortable gowning and working in a cleanroom environment or in a Biosafety Cabinet.
• Strong teamwork and communication skills.
• Preferred but not required:
  • Masters degree
  • Experience performing a complete NGS workflow: DNA extraction, library preparation, and running on Illumina platform machine. 
  • Experience extracting high MW DNA for long read sequencing. 
  • Experience with RNA extraction purification, reverse transcription and library preparation. 

Hiring Manager

Donna Hongo, Head of Quality, dhongo@myome.com

As our first Systems Architect & Engineer, you will define, design, implement, and operate the computing environment that enables our genomics health platform.  You will combine your technical skills, system architecture expertise, and passion for excellent engineering to help build a system to securely store, analyze, and utilize genomic and health information. The scope of the work includes security, cloud and system administration, monitoring, and deployments/devops. Your temperament should be nimble, flexible, pragmatic, and collaborative. You must be able to articulate a long-term vision, and deliver it incrementally through short-term milestones.

Key Responsibilities

• Comprehensive, hands-on management of our growing computing environment.
• Define, engineer, and manage our AWS computing infrastructure, including architecture, identity management, security policies and practices, cost reporting, and administration.
• Manage our Google Workspace, including account management and monitoring.
• Proactively identify and propose opportunities for improvement.
• Contribute to a supportive atmosphere of collective learning and development.
• As a well-rounded architect and engineer, be interested in our mission and committed to its success.

Ideal Skills and Experience

MyOme is looking for a world class Bioinformatics Software Engineer to join our team and impact the way genetic tests inform people about their health risks. Join an early stage startup with seasoned entrepreneurs and help build family planning and personal health platforms. As a bioinformatics software engineer, you will combine your technical skills, passion for excellent engineering, and bioinformatics expertise to write reliable, production-grade software to help build a system to store, analyze, and utilize genomics and health information. 

Key Responsibilities

• Work in a team to scope, define, and articulate solutions to complex computing and information management challenges.
• Lead and take ownership of key components that are appropriate for your skills and experience.
• Use your top-notch software engineering skills to develop robust, well-tested code.
• Contribute to the architecture and operations of our computing infrastructure.
• Contribute to a supportive atmosphere of collective learning and development.
• As a well-rounded engineer, participate in all aspects of the development process and be interested in our mission.

Skills and Experience

• No specific degree or field prerequisite. If you can do the work well and humbly, we want to talk with you.
• Excellent skills in Python and, ideally, familiarity with other languages.
• Experience with biological sequence data storage and analysis for genome interpretation, pharmacogenetics, and/or polygenic risk assessment.
• Experience with Linux/Unix and cloud computing and cluster orchestration, such as AWS EC2 and S3, Kubernetes/EKS, Docker, and related technologies.
• Experience with workflow systems, and ideally those used for bioinformatics and sequence analysis.
• Experience and comfort with modern software development, unit testing, CI/CD, and devops.
• Familiarity with information architecture strategies, ideally using a combination of relational, non-relational, and message schema tools.
• Ability to thrive in a nimble start-up environment with changing priorities. Know the difference between scrappy one-off code and production-grade code.
• Awesome if you have experience with any of: sequence analysis, ETL pipelines, analytics, ML/AI, system security, full-stack teamwork.

Physical Demands & Work Environment

• Duties are typically performed in an office setting when not in a pandemic.
• Duties may require working outside normal working hours (evenings and weekends) at times, e.g. to accommodate work across time-zones.